Tag: PLA2G4A

The demand for phenomics, a high-dimensional and high-throughput phenotyping method, has

The demand for phenomics, a high-dimensional and high-throughput phenotyping method, has been increasing in many fields of biology. Ohya Y. High-content, image-based screening for drug targets in yeast. PLoS One. 2010;5:e10177. [PMC free article] [PubMed]Ohya Y, Sese J, Yukawa M, Sano F, Nakatani Y, Saito 55-98-1 supplier TL, Saka A, Fukuda T, Ishihara S, Oka S, et al. High-dimensional and large-scale phenotyping of yeast mutants. Proc Natl Acad Sci USA. 2005;102:19015C19020. [PMC free article] [PubMed]Okada H, Abe M, Asakawa-Minemura M, Hirata A, Qadota H, Morishita K, Ohnuki S, Nogami S, Ohya Y. Multiple functional 55-98-1 supplier domains of the yeast l,3–glucan synthase subunit Fks1p revealed by quantitative phenotypic analysis of temperature-sensitive mutants. Genetics. 2010;184:1013C1024. [PMC free article] [PubMed]Okada H, Ohnuki S, Ohya Y. Quantification of cell, actin, and nuclear DNA morphology with high-throughput microscopy and CalMorph. Cold Spring Harb Protoc. 2015;2015:408C412. [PubMed]Okada H, Ohnuki S, Roncero C, Konopka JB, 55-98-1 supplier Ohya Y. Distinct functions of cell wall biogenesis in yeast morphogenesis as revealed by multivariate analysis of high-dimensional morphometric data. Mol Biol Cell. 2014;25:222C233. [PMC free article] [PubMed]Osman C, Noriega TR, Okreglak V, Fung JC, Walter P. Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion. Proc Natl Acad Sci USA. 2015;112:E947CE956. [PMC free article] [PubMed]Pardo-Martin C, Allalou A, Medina J, Eimon PM, W?hlby C, Fatih Yanik M. High-throughput hyperdimensional vertebrate phenotyping. Nat Commun. 2013;4:1467. [PMC free article] [PubMed]Piotrowski JS, Okada H, Lu F, Li SC, Hinchman L, Ranjan A, Smith DL, Higbee AJ, Ulbrich A, Coon JJ, et al. Plant-derived antifungal agent poacic acid targets -1,3-glucan. Proc Natl Acad Sci USA. 2015;112:E1490CE1497. [PMC free article] [PubMed]Rafelski SM, Viana MP, Zhang Y, Chan Y-HM, Thorn KS, Yam P, Fung JC, Li H, Costa L da F, Marshall PLA2G4A WF. Mitochondrial network size scaling in budding yeast. Science. 2012;338:822C824. [PMC free article] [PubMed]Rimon N, Schuldiner M. Getting the whole picture: combining throughput with content in microscopy. J Cell Sci. 2011;124:3743C3751. [PubMed]Skelly DA, Merrihew GE, Riffle M, Connelly CF, Kerr EO, Johansson M, Jaschob D, Graczyk B, Shulman NJ, Wakefield J, et al. Integrative phenomics discloses insight into the structure of phenotypic diversity in budding yeast. Genome Res. 2013;23:1496C1504. [PMC free article] [PubMed]Soifer I, Barkai N. Systematic identification of cell size regulators in budding yeast. Mol Syst Biol. 2014;10:761. [PMC free article] [PubMed]Sozzani R, Benfey PN. High-throughput phenotyping of multicellular organisms: finding the link between 55-98-1 supplier genotype and phenotype. Genome Biol. 2011;12:219. [PMC free article] [PubMed]Taylor RJ, Falconnet D, Niemist? A, Ramsey SA, Prinz S, Shmulevich I, Galitski T, Hansen 55-98-1 supplier CL. Dynamic analysis of MAPK signaling using a high-throughput microfluidic single-cell imaging platform. Proc Natl Acad Sci USA. 2009;106:3758C3763. [PMC free article] [PubMed]Tkach JM, Yimit A, Lee AY, Riffle M, Costanzo M, Jaschob D, Hendry JA, Ou J, Moffat J, Boone C, et al. Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol. 2012;14:966C976. [PMC free article] [PubMed]Vizeacoumar FJ, van Dyk N, FS Vizeacoumar, Cheung V, Li J, Sydorskyy Y, Case N, Li Z, Datti A, Nislow C, et al. Integrating high-throughput genetic conversation mapping and high-content screening to explore yeast spindle morphogenesis. J Cell Biol. 2010;188:69C81. [PMC free article] [PubMed]Wolinski H, Kolb D, Hermann S, Koning RI, Kohlwein SD. A role for seipin in lipid droplet dynamics and inheritance in yeast. J Cell Sci. 2011;124:3894C3904. [PubMed]Yang M, Ohnuki S, Ohya Y. Unveiling nonessential gene deletions that confer significant morphological phenotypes beyond natural yeast strains. BMC Genomics. 2014;15:932. [PMC free article] [PubMed]Yvert G, Ohnuki S, Nogami S, Imanaga Y, Fehrmann S, Schacherer J, Ohya Y. Single-cell phenomics discloses intra-species variation of phenotypic noise in yeast. BMC Syst Biol. 2013;7:54. [PMC free article] [PubMed]Zhou C, Slaughter BD, Unruh JR, Guo F, Yu Z, Mickey K, Narkar A, Ross RT, McClain M, Li R. Organelle-based aggregation and retention of damaged proteins in asymmetrically dividing cells. Cell. 2014;159:530C542. [PubMed].